产品货号：
Z13660
中文名称：
CDCP1抗体
英文名称：
Anti-CDCP1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CDCP1 Antibody |
| 指标别名 | CD318;CDCP1;Membrane glycoprotein gp140;SIMA135;TRASK |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | CDCP1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CDCP1 recombinant protein (Position:R582-T667).Human CDCP1 shares 84.5% amino acid (aa) sequence identity with mouse CDCP1. |
| 实际分子量 | 93～130KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | CUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene.It has also been designated as CD318 (cluster of differentiation 318) and Trask (Transmembrane and associated with src kinases).CDCP1/Trask is a 140kD transmembrane glycoprotein with a large extracellular domain (ECD) containing two CUB domains,and a smaller intracellular domain (ICD) containing five tyrosines.The tyrosine phosphorylation of Trask is tightly regulated and reciprocally linked with the state of cell adhesion.The tyrosine phosphorylation of CDCP1 in cultured cells occurs when cells are induced to detach by trypsin or EDTA,or seen spontaneously during mitotic detachment.The overexpression of CDCP1 leads to the loss of cell adhesion and a detached phenotype.CDCP1 is widely expressed in human epithelial tissues,but its phosphorylation is only seen in mitotically detached or shedding cells,consistent with its role in the negative regulation of cell adhesion. |
| Uniprot ID | Q9H5V8 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | CUB domain containing protein 1 |
| 蛋白名全称 | CUB domain-containing protein 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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